The Role of Gut Microbiota Modulation Strategies in Obesity: The Applications and Mechanisms

Nowadays, obesity is a leading public health problem worldwide. The growing prevalence of significantly accounts for other cardio-metabolic diseases, including hypertension and diabetes. Several studies have shown that strongly associated with genetic, environmental, lifestyle, dietary factors, especially the disordered profiles gut microbiota (GM). present review concluded mechanistic potential correspondent treatments obesity. Specifically, anti-obesity effects food-derived compounds manipulating GM were highlighted. limitations bioactive on absorption in intestinal tract also discussed. Thus, future direction fecal transplantation (FMT) as an approach to support modulating host (considered be therapeutic target obesity) was This shed light role modulation strategies prevention/treatment